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About cancer

Anal cancer

Anal cancer is a rare cancer that starts in the anus. This is where the bowel opens to the outside of the body. The main treatments are chemotherapy with radiotherapy (chemoradiotherapy) and surgery.

Anal cancer is different to cancer that starts in the back passage (rectum) or the large bowel (colon). These are called bowel cancer.

Read more about bowel cancer

What is anal cancer?

Anal cancer is when abnormal cells in the anus divide in an uncontrolled way. It can start in different parts of the anus and different types of cell.

Symptoms of anal cancer

Anal cancer symptoms may include bleeding, bowel changes and severe itching around the anus (pruritus). It is important to see your doctor if you have any of these symptoms.

Getting diagnosed with anal cancer

If you have symptoms of anal cancer you should see your GP. They might ask you to have some tests and may refer you to a specialist.

Stages and types of anal cancer

The stage of anal cancer tells you how big it is and whether it has spread. The type tells you which type of cell the cancer started in.

Risks and causes of anal cancer

The human papilloma virus (HPV) is the biggest risk factor for anal cancer. Other factors include getting older or having a weakened immune system.

Treatment for anal cancer

Treatments include radiotherapy with chemotherapy (chemoradiotherapy) and surgery. For advanced cancer you might have chemotherapy or radiotherapy on their own.

Last reviewed: 15 Aug 2025

Next review due: 15 Aug 2028

Reviewed by: 

This section has been written, reviewed and updated by Cancer Research UK’s Patient Information Web Team. Thanks to the expert medical professionals and people affected by cancer who have helped to review this information.

  • Joanna Thomson (Lower GI oncology Clinical Nurse Specialist)

  • Mr Peter Coyne (Consultant Colorectal Surgeon)

  • Anna Boyles (Lead Stoma Nurse)

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