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Bile duct cancer (cholangiocarcinoma)

Bile duct cancer is also called cholangiocarcinoma. It is a rare cancer that starts in the bile ducts. The bile ducts are small tubes that connect the liver and gallbladder to the small bowel.

What is bile duct cancer?

Bile duct cancer (cholangiocarcinoma) starts in the bile ducts. Bile ducts carry bile from your liver to your gallbladder. The gallbladder releases bile and it flows to the small bowel to break down fat in the food you eat.

Risks and causes of bile duct cancer

Factors that increase the risk of developing bile duct cancer include getting older and conditions that cause long term inflammation of the bile ducts.

Symptoms of bile duct cancer

Bile duct cancer symptoms may include yellowing of the skin and eyes (jaundice), itchy skin, dark urine and pale poo, high temperature and pain in your tummy (abdomen).

Stages and grades of bile duct cancer

The stage and grade of bile duct cancer help your doctor decide your treatment. They might use the number or TNM system, and the Bismuth-Corlette classification.

Types of bile duct cancer

There are 3 main types of bile duct cancer. Intrahepatic bile duct cancer starts in the liver. Perihilar and distal bile duct cancers start in the bile ducts outside the liver.

Getting diagnosed with bile duct cancer

If you have symptoms of bile duct cancer you should see your GP. They might ask you to have some tests and refer you to a specialist.

Last reviewed: 14 Oct 2024

Next review due: 14 Oct 2027

Page Credits: 

This section has been written, reviewed and updated by Cancer Research UK’s Patient Information Web Team. Thank you to the expert medical professionals and people affected by cancer who have helped to review this information.

  • Professor John Bridgewater (Consultant Oncologist)

  • Professor Brian Davidson (Consultant Hepatopancreatobiliary Surgeon)

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