Bladder cancer

Risks and causes of bladder cancer

Smoking tobacco is the biggest preventable cause of bladder cancer in the UK. There are some other risk factors that can increase your risk of developing bladder cancer.

What is a risk factor?

Anything that can increase your risk of getting a disease is called a risk factor. Different cancers have different risk factors. Having one or more of these risk factors doesn't mean you will definitely get that cancer. The risk factors for bladder cancer include:

Smoking

Smoking cigarettes increases the risk of bladder cancer. Around half of all bladder cancers in the UK are caused by smoking. 

Your risk of getting bladder cancer if you smoke is up to 4 times that of someone who has never smoked. Smoking other types of tobacco products, such as cigars and pipes, also increases your risk.

Stopping smoking can reduce your risk of bladder cancer, compared with your risk if you continue to smoke.

Read more about smoking and cancer, including how to stop smoking

Chemicals at work

Exposure to chemicals in the workplace causes around 5 out of 100 cases of bladder cancer in the UK (around 5%). Higher bladder cancer risk in some occupations may also be partly due to smoking.

Certain types of jobs carry a higher risk than others, depending on the exposures people may have. But these days, if people work with dangerous chemicals there are regulations to keep their exposure within safety limits.

Chemicals that are linked to an increased risk of bladder cancer include:

  • aromatic amines

  • polycyclic aromatic hydrocarbons

  • mineral oils

Aromatic amines

This is a group of chemicals known to cause bladder cancer. Some of these chemicals have been banned in the UK for over 50 years. But you may have been exposed to them if you work in industries that produce dyes, rubber or textiles. It can take around 30 to 40 years or more for a bladder cancer to develop after exposure.

Polycyclic aromatic hydrocarbons (PAH)

These are a group of chemicals that might increase the risk of bladder cancer. You may have been exposed to them if you have worked in:

  • industries where people handle carbon or crude oil, or substances made from them, such as petrol

  • any industry involving combustion, such as smelting

Mineral oils

Exposure to mineral oils in some workplaces, including metalworking and aluminium production, may increase the risk of bladder cancer.

Long term bladder irritation or inflammation

Long term (chronic) bladder irritation or inflammation is linked with an increased risk of bladder cancer. Causes of chronic bladder irritation include:

  • repeated urinary tract infections

  • bladder stones

  • having a catheter in the bladder for a long time

An infection called schistosomiasis (bilharzia) is a known risk factor for bladder cancer. The infection is caused by a parasitic worm that lives in fresh water in some parts of the world, including Africa and Asia. But this parasitic infection is extremely rare in the UK.

Previous radiotherapy for cancer

Your risk of developing bladder cancer is higher if you have had radiotherapy in the past to treat cancer in your . For example, prostate cancer. This risk may be less with newer radiotherapy techniques. But longer term research is needed.

Family history

You might have a slight increase in risk of bladder cancer if you have a first degree relative with bladder cancer. First degree means a parent, child, sister or brother. This might be because of genetic factors or because you share certain behaviours such as smoking, which increases your risk.

Are there other causes?

Stories about possible cancer causes are often in the media and it can be hard to know what's true and what's not. You may have heard of something that isn't included here. This is because we only include a risk factor if it is supported by good quality evidence.

Find out about common cancer myths and questions on the causes of cancer

More information on risk factors for bladder cancer

We have more detailed information for health professionals about bladder cancer risks and causes.

For detailed information go to the Cancer Statistics section

Last reviewed: 06 Aug 2026

Next review due: 06 Aug 2029

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