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Types of neuroendocrine cancer

Pancreatic neuroendocrine cancers

Pancreatic neuroendocrine cancers develops in in the . You might also hear them called pancreatic neuroendocrine neoplasms (NENs). This means the same as neuroendocrine cancer.

There are 2 key groups of pancreatic neuroendocrine cancer:

  • pancreatic )

  • pancreatic )

NETs and NECs are very different. So it is important to know which one you have. Talk to your doctor or specialist nurse if you are not sure.

Doctors group pancreatic NETs as either functioning NETs or non functioning NETs. This depends on whether the NET makes and releases abnormal levels of . The main types of functioning pancreatic NETs are insulinoma, gastrinoma, somatostatinoma, glucagonoma and VIPoma.

Pancreatic neuroendocrine cancers are rare and need different treatment to the more common type of pancreatic cancer. 

We have information about pancreatic cancer here

What are pancreatic neuroendocrine cancers?

Pancreatic neuroendocrine cancers are rare cancers that start in the neuroendocrine cells of the pancreas. There are many different types.

Grades, types and stages of pancreatic neuroendocrine cancer

Grade means how quickly or slowly the cancer cells are dividing and growing. The stage of a neuroendocrine cancer tells you its size and whether it has spread. There are many different types.

Non functioning pancreatic neuroendocrine tumours (NETs)

Non functioning pancreatic NETs are the most common type of pancreatic NET. Non functioning means they don’t over produce hormones, or cause a set of symptoms (syndrome).

Insulinoma

Insulinomas are rare neuroendocrine tumours (NETs) that start in the pancreas. They make the hormone insulin which controls the amount of sugar (glucose) in your body.

Gastrinoma

Gastrinomas are rare neuroendocrine tumours (NETs) that develop in the pancreas or duodenum. They make large amounts of the hormone gastrin.

Glucagonoma

Glucagonomas are very rare NETs that develop in the pancreas. Glucagonomas usually make large amounts of glucagon which raises your blood sugar levels.

Last reviewed: 05 Mar 2025

Next review due: 05 Mar 2028

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