Individual therapies
Chaparral is a herb. It comes from the creosote bush in the western deserts of the USA.
Summary
Chaparral is a herb
There is no scientific evidence to support its use as a treatment for cancer
Chaparral can have severe side effects
Chaparral is a herb that comes from the creosote bush. It grows in the western deserts of the USA.
Native Americans have used chaparral for many years to relieve pain and inflammation. They also use it to treat many illnesses. These include colds, diabetes, digestive problems and cancer.
In traditional medicine chaparral tea is used to treat gallbladder and kidney stones.
Many internet sites advertise and promote it as a way to treat or prevent cancer. But there is no research to prove that it works or if it is safe to use. There is no scientific evidence to support its use for the treatment of cancer.
Chaparral contains lignans. Lignans are chemicals found in plants. They have oestrogenic and anticancer effects.
The main lignan in chaparral is nordihydroguaiaretic acid (NDGA). It is a potent antioxidant. That means it protects cells from damage. Despite it being an antioxidant, it is toxic. In high doses NDGA causes liver damage.
M4N is a chemical made from NDGA. It is also called a derivative from NDGA. Researchers have tested M4N in laboratory studies on mouse and human cancer cells. They found that M4N can stop cancer cells from growing.
You can buy chaparral from health food shops, pharmacies and over the internet as:
tablets or capsules
dried leaves for making tea
liquid (tincture) made from chaparral leaves dissolved in alcohol
capsules with added antioxidants such as vitamin C
The US Food and Drug Administration (FDA) advises against swallowing or injecting chaparral. It is toxic and can cause severe and permanent kidney and liver damage, even death.
In 1992, the Food and Drug Administration (FDA) in the USA sent out a warning. They wanted to encourage the removal of all chaparral products from the market. In 2005, Health Canada also issued a warning not to take products containing chaparral. Despite this, chaparral is still easy to buy in shops and over the internet.
Chaparral can also cause:
diarrhoea
weight loss
fever
skin rashes and itching
tiredness
acute inflammation of the liver (hepatitis)
kidney cysts
tummy pain
You shouldn’t use chaparral if you:
are pregnant or breastfeeding
have kidney or liver problems
are taking certain medicines
are diabetic – in animal studies chaparral has lowered blood sugar levels
are trying to become pregnant – chaparral may prevent ovulation which will lower your chance of getting pregnant
Chaparral can interfere with how some drugs work. Especially those that can also affect your liver and kidneys. These include:
some antibiotics
non steroidal anti inflammatory drugs such as ibuprofen
a type of anti depressant called a monoamine oxidase inhibitor (MAOI)
Children shouldn’t have chaparral. This is because of the possible side effects and the lack of scientific data to prove that it is safe.
Be cautious about believing information or paying for alternative cancer therapy on the internet.
Only buy products that are registered under the Traditional Herbal Remedies (THR) scheme - these have been tested for quality and safety.
Read more about the cost of complementary and alternative therapies
It is understandable that you might want to try anything if you think it might help treat or cure your cancer. Only you can decide whether to use an alternative cancer therapy such as the chaparral.
You could harm your health if you stop your cancer treatment for an unproven treatment.
Many websites might promote chaparral as a cure for cancer. But no reputable scientific cancer organisations support any of these claims.
Last reviewed: 16 Aug 2022
Next review due: 16 Aug 2025
Find detailed information and research into some of the many different complementary and alternative therapies used by people with cancer.
A complementary therapy means you can use it alongside your conventional medical treatment. It may help you to feel better and cope better with your cancer and treatment. An alternative therapy is generally used instead of conventional medical treatment.
This section has information about the safety of complementary cancer therapies and alternative cancer therapies.
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